What I do think is, in 15/20 years, Bryan could come back and make his X3. Obviously, with new actors.
As for a next team movie, I just want an X4, or, very remotely, a reboot. Disregarding X3 isn't the way to go. The genreal audience does remember X3, and they seem to like it a lot. The x-movies are already a bit confusing for those who don't follow, just imagine forgeting a whole movie. It would be mind breaking.
So yeah, bring on an X4, and do the "X-Men return" trick in some decades. I still want to see my Phoenix bird one day, damnit