Originally Posted by MikeFrost
No real impact except that it needs to be a hero to replace him. There's a whole important point on the script of Colossus nagging Deadpool to be a good guy and doing the right thing.
So it basically needs to be a by-the-book good guy with a ****load of strength.
Cool. Sounds good to me. Deadpool fighting Colossos morally and physically could be hilarious.