The #4 movie - which movie series will have it first?
X-Men - Wolverine and First Class are prequels, so technically they aren't "X-Men 4"
Spider-Man - the fourth movie from Sony is a reboot
Blade - no news about Blade 4
The Avengers - too early to tell
Fantastic Four - the third movie from FOX will be a reboot
Iron Man - very possible unless Marvel Studios doesn't want to continue the Iron Man movie series after IR3.
I'm going with Iron Man.
X-MEN RI5E' MUTANT OF THE MONTH | PROFESSOR X | PORTRAYED BY PATRICK STEWART
"Every few hundred millenia evolution leaps forward." - X1
"Sharing the world has never been humanity's defining attribute." - X2
"Will you control that power or let it control you?" - X3
"Is the future truly set?" - X4