Yeah, interesting interview.
Makes it clear that the Malibu attack happens early in the movie, and it sounds like the majority of the movie is Tony having to operate without much in the way of resources, including his suit(s).
You left out another important quote from the interview:
"Characters like James Bond and Batman, whose stories go on and on and on — I think Tony is one of those characters. Where we go directly after Iron Man 3 ... I'm not looking too far ahead. I'm looking to finish Iron Man 3, getting into Avengers 2, and then seeing where we go from there. But I do think we have more Tony Stark tales to tell, and we'll take it one movie — or maybe two movies — at a time."
Pretty much confirms that Iron Man will be in Avengers 2, no surprise; but it's still unclear if RDJ will be in the suit, or if the recast will happen then.