Just thought about something interesting. If this were to be picked up for a full season order, then it would run through Thor 2 and, more specifically, Cap 2, which has a very big SHIELD presence in it, almost to the point of being a SHIELD movie. I can't imagine Marvel not attempting do some kind of overlap, especially for Cap 2...I mean, they even hired an ABC lead star to play Sharon Carter.
I think if Van Camp is playing Sharon Carter, then there is probably a good possibility that she could appear on the show. Just as you mentioned, Thor 2 and Cap 2 would premier during the airing of SHIELD, so I would expect some overlap and references to these films. It would be quite exciting.