Re: Captain America 3 Villian
Well it obviously depends on the fallout from CA:TWS (I've been staying fairly spoiler free on that one), but I'd like to see Sin & Crossbones as the main villains on a quest to resurrect Red Skull. It might make more sense to make Sin the Red Skull's granddaughter in the MCU, but I've always enjoyed the characterizations of her & Crossbones in Brubaker's run. A 'Natural Born Killers' vibe would be an interesting dynamic, especially since it might allow Sharon Carter to take on a larger role as a foil to Sin.
Zemo or Strucker would be good as the modern front for HYDRA also - I like the way they were portrayed in EMH, so there's something to draw from already.