Any time I do something I think it through to the end, in theory the most realistic end using information available in the moment. Not what you hope will happen (it rarely does) and not the worst case scenario (seldom happens but never rule it out) IF after that thought process it still seems like a good idea then by all means jump in 100%, if you can taste trouble in the wind however, avoid that at all costs, better safe than sorry is one of the wisest pieces of advice I got from my Grandparents.
The USA (Marvel & DC, etc) no longer exists but the world needs heroes, who would you put together to be a team of international heroes to defend the world?