Well, finished Revelations....Wowsers. Great freaking story, really enjoyed the ending too. Can't wait for 3 and I feel like I can very, very confidently say that a majority of the next game will definitely be Desmond in modern times. I mean, it really naturally leads into that, as most of us speculated, but not only that, when it ends, you DESPERATELY want to follow it on. I mean, I can't see too many people being disappointed at the prospect of finding out what comes next in modern times with the way Revelations ends, and it still most definitely opens itself up to some historical Animus usage too.
Also, I wouldn't read into the Egypt thing. The supposed 'spoiler' at the ending that hints Egypt is literally just a character referencing Alexandria, but there is no reason at all we would expect to have to go there, especially not Ancient Egypt, since that would be well before when it is referenced anyway. Plenty of other places are referenced in this game, France, China, Britain, i mean A LOT of places, so it really could be anywhere.