Why have Bizarro at all? Why not just use Brandon if you feel we have to have Bizarro. Last I heard, Fraser was being considered for Bruce Banner in the relaunch of The Hulk (Another bad casting for that point, too)
If you're going to do a sequel, use Brainiac. Better yet, get rid of his most famous villain. Bryan Singer and the whack pack Harris & Daugherty. Those three have hurt Superman more than Lex, Darkseid, and Brainiac ever have with Superman Returns.
The best thing that could happen is to quietly relaunch the franchise a few years from now with a Post-Crisis version, and reunite Timm/Dini, and get rid of Jason.
Just start fresh. Superman deserves better than Bryan Singer. He had his chance and dropped the ball. POTC 2 is proving this weekend what it takes to make a great epic action film. It's everything SR isn't.