The MCU has tie in comics. They never really go too deep and are usually just recaps and small one shots. Then again Spider-Man has specials powers when it comes to crossovers with other Spider-Men. The PS4 Spider-Man was made canon in the comics just because he was so popular. So let's see how the Spider-Men are treated and more importantly how they act afterward. The two could have no interest in returning to the role. Also knowing Disneys reputation, these actors are gonna ask for some bank. Let's no forget these two are award winners and nominees. Then knowing the previous Sony relationships and trials I highly doubt they'd wanna risk it again without substantial compensation. Again cameos being the exception because they require less paper work.