Hell's Kitchen?
Despite what comic books say, if THAT'S Hell's Kitchen, then put me in the pantry, with all the grimy coffee shops, and intensely dangerous outdoor seating for the Italian restaurants and hookah bars. And then there are the gangs running through there--you've got The Daily Show, Colbert Report, Letterman...
Yes, parts of Harlem still have an edge, but for better or worse, Manhattan has been the realm of the rich or richer since Giuliani Time. But that is getting off topic, I suspect.