Bigger Sentinels
Brotherhood of evil mutants, but maybe a different take?
I really want to see the Blob on the big screen. They could do it sensibly, without insulting any particular demographic group. I like the scene where he's up against Rogue here. I really like his humor in general. He's good comic relief in Legends I.
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Also, still hoping to get the Rogue-Magneto-Gambit triangle, Whedon's Emma Frost, Archangel,
Since the 2014 film, the franchise may have lost its social tones a bit. I personally don't mind the human characters at all and, in fact, not only should they keep using human villains like Trask and Stryker, there should be human-mutant friendships in the films.
Eventually, I would like to see Magneto build a mutant nation, either Asteroid M or Genosha. But you can't do this without humans. It would be awkward like Apocalypse was.