I think we should see some unused villains. Everyone knows Osborne is the Green Goblin but that doesnt mean that just because he is in the movie that the Goblin must also be there. Spend some time building up his character and relationship to Peter. Look at what Batman Begins did for Scarecrow and Ra's Al Ghul, neither of which are A-List Batman villains but they did a great job of being bad guys in that film.
