Hmm, I like Batman so much, and the new The Shadow is also amazing. So it would definitely be a dark noir-esque comic. I think the main character should have a super power, though. But it should be something that the main character doesn't normally have in comic books, or maybe even a power that is pretty rare in comic books. It's hard to think of one that hasn't been done to death...I like intangibility. There's quite a few things you can do with that, having the character gradually learn to walk through walls, float/fly, etc. Villains should be mobster-esque but the main guy needs to actually look like a superhero, though. Like blue-body suit type of stuff. Not like the Shadow where he's in a trenchcoat get-up or whatever.
I also kind of like that thing where he's like the first superhero in an otherwise normal world and he really eventually overturns a lot of societal conventions. People view him as a huge threat and so forth. Watchmen-esque, I guess.
For setting I'd like that Batman: TAS thing, there are computers and TVs but everybody drives 1950s cars and shoots tommy guns. Futuristic monorails next to grimy tenement buildings, that sort of thing.
EDIT: Oh, guy needs a weakness. Uh, he's weak to electricity, radio waves, and such. It can harm him even when he's intangible. The villains eventually figure this out and come after him with lightning guns, try to microwave him, etc. I'd kind of like to see one where the hero gets more and more godlike as the series goes on, though, and he overcomes this weakness and learns to control it, redirecting electricity, etc. Eventually he's so powerful and skilled that he's viewed as a threat by the military and such. Kind of like Dr. Manhattan except a gradual evolution to that point.
I also think that while it should be a long-running series it needs to definitely be scripted out with the ending decided upon when they begin and major milestones planned out. It should be created with the idea that it will eventually end, even if it's ten years later.