I hope I'm proven wrong, but conceptually if true (and that includes the basics of the story as being reported), this sounds just plain dumb to me.
I hope the battling Swat members with Lizard/beast like symptoms means he stumbles across some held hostage in the Lizard's Lair, and tries to free them before he realizes the Lizard has done "experiments gone wrong" on them (some in various stages of failed state.. some more than others) and frees them to only find out... He's not in Kansas anymore. Or.. all hell breaks loose when he frees what he thinks will be grateful captives only to find out otherwise.
Now.. that SMACKs against his Spider-Sense... (but one can ignore Spider Sense in the heat of the moment I guess, or misinterprupt it to be the actual Lizard lurking nearby and not realize it's the captives) so that approach could work, and could be a really cool scene.
I'm hoping.. NO army of Lizard Men though, and DEFINITELY no quick transformation.