This new photo with the "warehouse" background looks like it might be the original, with less manipulation. In any case, It has better resolution than the one with the "Baxter Building".
I like how the Fantastic Four look. They have changed the Thing a bit, but I thought he was fine in the first movie, so it's no biggie. Johnny and Reed look fine also, no big changes. The biggest change seems to be with Sue. I'm going to say I liked her hairstyle in the first movie better. In this newest picture it isn't bad though. It does look like Alba has lost some weight compared to 2 years ago, but with the "muscle suit" she doesn't look scrawny at all.
I'm not going to make any real conclusions until the trailer, just like everyone else. I don't trust these photo-manips much. The people who make them are quite talented, but they are really just a hint at what we will see on the screen.