I do like the idea of spider man being the focus, but I HIGHLY doubt that will happen. Especially because they have already announced that it will be a captain america movie, as well as the storyline was written before they were even planning on having spider man. There is enough time to rescript some stuff and add in spiderman, but I don't think they would have enough time to rescript it all from spidermans perspective.
That being said, the movie is almost certainly going to be 'from captain america's perspective'. But that doesn't mean they are going to make all anti registration look like bad guys! I think plenty of times bad things have happened in the comics, and the MCU that were a hero's fault, and NO ONE blamed the hero. Iron Man thinks it's a good idea to have registration, and if that ends up backfiring, as the captain thinks will happen, then it IS NOT fully his fault. He was doing what he thought was best, even if he was blind.
(Kinda like how some people are talking about the U.S. President, some say he made no mistake, some say he made a mistake and it wasn't his fault because he didn't know, and some say he did know and he has made a mistake. On any given issue.)
I personally hope that IF they MUST kill Steve Rogers, Bucky along with others should help make sure that the Steve's legend lives on, and the idea of freedom, liberty, and the idea that those are more important than trying to make the world perfect. Either way it seems they will have to make it so that the registration act is not a good idea. Otherwise Cap's death is useless. His fighting would be seen as irrational, he would have been completely wrong to fight, and his death would have been in vain. We CAN'T have that happen. If he dies and then Stark decides against registration, then Starks fighting was in vain, and therefore it puts a little more 'fault' on Tony Stark. What they need to do is make the registration a bad idea, but make it seem more like the whole Hydra issue, it was all behind the scenes and was too hard for Stark to see it was a problem. Stark would have the same guilt on his shoulders that Nick Fury had, he feels slightly responsible, but he knows it wasn't really his fault. The fight for registration is successful, but when and if it backfires, Tony sees that all his work in fighting for registration has been dumped down the drain but has also been turned into something bad.