I gotta say, I'd rather just see a massive New York city. Freeroam. Full control of my web swinging. Not the crap we got in The Amazing Spider-Man game. multiple costumes. a good story. exciting combat and gameplay. a sense of speed and motion. a large open, living New York city. id like to see this New York with a feel like GTA 4.
there are so many more things I'd like to see, but sadly it'll just never be the case.
Oh I'd also like to see some type of co-op mode as an extra. I mean there are so many other playable characters that could be used. Venom (it had to be said), Scarlet Spider, Ricochet, Dusk, Prodigy, Hornet, Black Cat, Daredevil. And in case you can't tell, I'd love the game to be a bit of a throw back to the 90's Spider-Man comics.
I'd also love to be able to live as Peter Parker also. Have to protect your identity, take photos and also build devices.