Tried to go for ones I hadn't seen in the topic too.
Tuco - The Good, The Bad, and The Ugly
All the Mains in Once Upon A Time in the West
Fievel - In An American Tail 1, he grows up. In 2, he becomes a hero.
Judge Claude Frollo - The Hunchback of Notre Dame
Quasimodo - the Hunchback of Notre Dame
Charlie - All Dogs Go To Heaven
Simba - The Lion King
Bernard - The Rescuers Down Under
Han Solo - A New Hope and Empire Strikes Back
Luke Skywalker - All Star Wars Films
No Name - Sword of the Stranger
The Blond Demon - Sword of the Stranger
Indiana Jones - The Last Crusade
Stanley - The Bellboy; he spends the entire movie never saying a word, finally shocking his so-called superiors and everyone around him with the fact he CAN speak.
Professor Kelp - The Nutty Professor (original)
The Grinch - How the Grinch Stole Christmas
Kevin McCallister - Home Alone 1 and 2
Salieri - Amadeus
Captain Jack Sparrow - The Curse of the Black Pearl
Scout - To Kill A Mockingbird
Rincewind - The Colour of Magic
Frodo - The Lord of the Rings
Dobbs - Treasure of the Sierra Madre