I can't decide the actor now. I will say that he's a must for Netflix, so the character can express himself and what he deals with on a daily. I could see them easing him into a series like Punisher in DD S2 and then giving him his own series.
I'd love for a Moon Knight series and Nightstalkers, what with Doctor Strange and the strong possibility of the Midnight Sons coming into play. I say have the 90s team of Nightstalkers with Blade, Hannibal King and Drake, descendent of Dracula, in the team. Have Dracula and Bloodstorm and Lilith and Varnae in the fray. Having Hannibal and Drake going out in style by season 1's end, maybe? Bloodstorm, a chaotic character with Dracula powers, being take down by Hannibal. He pulls them both into the dawning sun or something. Frank Drake, like he did in the comic, creates his famous gun called Linda (after Linda Blair), to take on supernatural beings, amps it up to take on and overload during the fight with Varnae, the ancient demon that created the vampire curse. It explodes and leaves Blade the sole survivor of Nightstalkers. He could come across others, like Whistler's daughter and Morbius, in the future seasons as he hunts for Dracula and his daughter, Lilith. The now crowned king and princess to the vampire curse.