Stan Lee is the only comics creator I can think of whose fame extends so far into the non-comic book reading public. As fans we know the giants of 'our' industry, names like Kane & Finger, Siegel & Shuster, Kirby, Ditko, Infantino, and then later Moore, Waid, Morrison, etc. But many, many people who've never read a comic book or seen a CBM in their lives know who Stan Lee was. His was the single greatest contribution to comic books/comic book characters achieving the enormous popularity they have today.
RIP (and thanks) to a true legend.