Shocker is a Romita villain, his first appearance is Amazing 46.
Spencer Smythe was made during the Lee/Ditko era, introduced in Amazing #025.
Alistair was introduced in Annual #19.
John Jameson was introduced in issue #001 of Amazing, his first appearance as Man-Wolf was in issue 124, during the Conway/Kane era, at the gate of Andru's run start.