I think if you were to do Kraven, you should make him a bit more akin to the original Predator film. He's a stealth, un-stopable force of playing a game of cat and mouse with Peter Parker, studying him , attacking his Spiderman and Peter Parker persona. Always a few steps ahead of him, even taking out Spiderman's foes in order , until he pounces ala Kraven's Last hunt. I think he should even be more than just a human , in addition to having different animal splices in his DNA which not only would give him equal footing but would give his interactions a very primal vibe. I think you could even do it without him being a hired gun or wanting to destroy the city kinda stuff. Make him a man obsessed and driven to personally destroy Spiderman. That's how I'd do it anyway.