Well again not everyone has complete monsters in their rogues galleries. Though it did seem that William Stryker was somewhat less evil in the movies then the comics, but he was still very unlikable in the movies.
I liked Dr. Octopus being an anti villain in the movie, because he has gotten plenty of pet the dog moments since the 80s, ditto with Sandman who is often an Anti Villain in the comics, though the execution is a bit off in the movie with him. With Sadman the cocnept was sound, but the execution fell flat.
Joker in TDK was pretty damn close to being a complete monster though, he is not sympathetic at all. Also when Red Skull appears in the Cap movie, he will have to be completely evil. Bullseye had a personality close to his comic book counterpart, he seemed like a complete monster.
I'm more unhappy that both Doom and Lex were not Magnificent Bastards in the movies, they are epic schemers in the comics and in the movies they fall way short. Movie Doom is just some base, creepy smug snake and Lex was a cackling card carrying villain. We need more Magnificent Bastards in these movies.