I know wikipedia isn't always reliable, but this is in the Friend or Foe page:
Choose a sidekick from your allies Pick from a long list of Spider-Man's allies like Blade, Iron Fist, The Prowler and swap between sidekicks at any time. Spider-Man and any chosen sidekick can unleash lethal combos against opponents.
Fight against movie villains, then alongside them Face off against infamous movie villains using an innovative combat system. Combat Doc Ock in his lab, Sandman in a construction site, and the Green Goblin on the rooftop of Oscorp. Then turn bad guys into good. Once defeated, they become your sidekicks.
Team up in two-player co-op Share the fun with a friend or sibling! One of you plays Spider-Man and the other controls one of Spider-Man's powerful sidekicks. You can play Co-operatively through every world, area and level. Team up to accomplish more powerful moves that will blow away the villains.
Enjoy details inspired by the Spider-Man movies Movie villains are just the beginning. You also get to experience costumes, battle scenes and spoofed scenes, all inspired by the first three Spider-Man films.
Come back for more, again and again Replay each chapter with a different sidekick and eventually with Black-Suited Spider-Man. Unlock additional characters such as New Goblin and Silver Sable. Fight in diverse worlds, from an island jungle and a New York training ground to Transylvania and Nepal.