Ok, so, my first impression.
The antagonist that gets the whole thing started is weak. A star going nova threatening to destroy the galaxy? There are ways a star going nova can be a significant threat. These include things like the obvious expanding star and radiation, to a massive gamma ray burst.
But all of these things have one crucial limit. They can't travel beyond the speed of light. So, yes, a massive solar flare may be able to wipe out a small planet in a few minutes. If it was close enough to the star. But it would take years for it to effect Romulus. Even if Romulus was the neighboring start system, it would be a couple of light years away. So they'd have years to prepare and evacuate, not days or weeks.
Of course, this is the Trek universe. So maybe this massive star's nova disrupted subspace or something. The disruption could travel faster than light, and the time frame works out.
But it seems in the comic that the star is actually growing to be light years wide, at faster than the speed of light. Everything about that is wrong. All of these problems could have been avoided by just saying one of the stars in the Romulan home system (it's a binary star system) is going nova instead.
And then there's the red matter. Not only could they have found a better name, but why make up a new type of matter? Why not just use something like dark matter? Or say the Decalithium (which I'm guessing is eight better than dilithium

) can be used to cause an implosion in the Hobus, that will cause it to collapse on itself into a black hole.
Ok, that's my nitpicking of the weak parts. Nero's motivation against the Federation and Vulcan makes sense now. And it's given me enough to start guessing at spoilers for the movie without actually giving anything away. I especially liked the explanation for the Nerada. When I first saw pictures of it, it didn't make much since. Why would a ship need spires like that, especially given the ship designs we've seen throughout Trek history. Now it can be explained as Borg adaptation technology altering the ship in ways we might not understand. I can live with that. Also makes me wonder how the hell the 22nd century Enterprise is going to stand a chance against it in the film.
I'm liking seeing the old characters come back and what's been happening in the Federation since Voyager. The Romulans becoming less xenophobic after the Dominion War and opening up formal relations with the Federation is good to see. And logical since the war would have been lost without the thre superpower (Feds, Klingons, Romulans) banding together. And Spock is finally the official Federation Ambassador to the Romulan Empire.
I like how they've pretty much officially canonized that Data's transfer of memory to B-4 worked. Data still died in Nemesis, but a backup copy survived (the advantage of being an android).
Picard is thankfully not an Admiral (always take Kirk's advice on such matters). I certainly wasn't expecting him to be ambassador to Vulcan, but it seems a good fit with his prior experiences with Sarek and Spock.
And in the next issue we get to see
General Worf! Although I liked the idea of him being ambassador to the Federation, Worf needs to be out their in the thick of the action.
So, those are my first thoughts.