Spidey is about 20-25x as strong as Wolverine and is 15x as fast as human optimal. Wolverine may be twice as fast as human optimal. As for skill, Spidey has superhuman coordination as well as his speed. This means that he can easily perform physical feats that others take years to learn and even things that others can never learn to do. Spidey has fought martial arts trained opponents before and can easily do anything he has seen them do. Marvel has said that he is highly skilled in hth in addition to his powers. In a fight in Berlin Spidey and Wolvie both went berserk and went at each other on the ground within arms reach. Spidey hit Wolvie at will, Wolvie couldn't touch Spidey at all. With Spidey's speed and strength, if he wanted to kill, he could simply slap Wolvie's head right off of his shoulders and Wolvie would never even see it happen.