****, no! When Miller is on form, there's no one like him but he's not a versatile writer. He only has one style... And that style wouldn't work for Spider-Man.
I think he'd write New York really well... But Miller can do that in his sleep. The problem is Spidey'd be swinging around helping heroin addicted prostitutes and fighting "no-good street Punks"...
Everything would feel weirdly different.