At this point, i just want to see Blade and Fantastic 4 do big numbers at the boX office, given that they didn't really perform that close compare to the X-Men and Spider-Man in the 2000s. Though the first Fantastic 4 film did well despite the reviews.
Guardians is fine. Its the last film for them (that we know of). Marvels is a sequel to a billion dollar grossing film and should be fine. Deadpool will be fine. Avengers 5 and 6 will perform big regardless how phase 5 and 6 movies turned out to be.
I don't care about Captain America 4 since its a legacy character film. While Thunderbolts is consisting of supporting characters we have seen too many times before. I don't think there's a lot riding on those two films.
X-Men and the sequels for Shang-Chi, Eternals, Multiverse of Madness and Wakanda Forever should come out in the not so distant future. But the X-Men is The one to watch out as that would really open to a lot of possibilities to the future of the MCU.