Here is a pseudoscientific explanation for how Isaac's precognitive ability might work:
In the laws of physics, there are four known fundamental forces. The four forces are: the electromagnetic force, the weak nuclear force, the strong nuclear force, and gravity. The strong nuclear force holds together positively charged protons and neutral neutrons in the nuclei of atoms. The weak nuclear force controls the radioactive decay of atoms. The other two forces can operate on larger scales. Electromagnetism attracts negatively charged electrons and positively charged protons to each other, creating atoms and molecules and all matter. Gravity governs all matter, drawing it together, creating the structure of every star system and the universe.
There also exist a fifth force, a quantum potential force field that pervades all space. This force acts on us at all times. It acts on every particle in every atom in our bodies. And on every particle in every atom in everything else in the universe. It surrounds us and penetrates us; it binds the universe together.
The odd effects of quantum mechanics arise because each particle is accompanied and governed by a wave in this quantum potential field. This quantum potential wave is part of a physical force field, like a gravitational field, that affects the course of particles.
This force does not decrease with distance, unlike other forces. A single quantum potential wave controls the two entangled particles, no matter how far apart they go. Measuring a property, such as the spin of one particle, instantaneously alters the shape of the wave, affecting the other particle under its control. So the quantum potential force violates both locality and independence. The quantum potential field conveys any change instantaneously over all of space because it carries information about the whole universe.
Simply put, the quantum potential field is a continuous field throughout the universe that acts instantaneously throughout the universe. It is not created by or concentrated around matter, unlike other forces. Although the quantum potential force guides particles, it is not generated by them.
Because the quantum potential force permeates all space and is not affected by distance, it in essence entangles or interconnects all particles. The universe is not a collection of objects, but a web of vibrating interconnected patterns governed by this quantum potential force. Unlike the other forces, the quantum potential has no known physical source and the quantum potential force violates locality.
Just as space and time are interconnected as part of a space-time continuum, everything is connected as part of a single continuum. The entire universe is one single, complex entity. The whole universe is enfolded in everything and each thing is enfolded in the whole; and it is the quantum potential force that controls and connects all things.
As human consciousness is one piece of the unified universe, Isaac can subconsciously "see" through the seemingly chaotic physical universe to the true order and nature enfolded in the universe. On a subconscious level, he observes this order and is a part of it. He is connected to all things and is unconsciously aware of the position and velocity of every particle in the universe at any given moment, enabling his subconscious mind to accurately predict their probable interactions. In layman's terms, because Isaac has information about literally everything in the universe his subconscious can logically deduce actions that are nearly 100 percent certain to happen. This means his subconscious can determine the future history of the world for weeks to come. His mind can store this much information because the emergent property of human consciousness is more than the sum of neuroelectrical activity, the subconscious mind works on a quantum level as well; it extends beyond the mere organic.
Just as various things in our subconscious are picked up by our conscious mind, some predictions that are especially notable to Isaac's psyche are picked up by his conscious mind in a subtle manner, i.e. he can visualize some predictions while painting.
Although the Heisenberg uncertainty principle accerts that it is impossible to look at a sub-atomic particle and know both where it is and where it's going at the same time with exactly 100 percent accuracy, Isaac's subconscious still calculates probabilities to a 99.999 percent level of likelihood. The 0.001 probability is only actualized by something that prevents the 99.999 probability as a result of Isaac's interference because of his vision. This means that unless Isaac tries to prevent one of his visions or makes others aware of it, the chances become 100 percent the prediction will happen.