The Justice League assembles at the Watchtower. J'onn and Palmer are monitoring the situation when Diana arrives, asking Superman's whereabouts. J'onn says that he cannot detect Superman's mind through the chaos that has enveloped the Earth. We see a glimpse of what he's talking about.
Diana joins Green Lantern, The Flash and O'Brian on the roof of the Watchtower. Green Lantern has set a giant floodlamp over Metropolis. There is looting and rioting here, too. Diana points out that they must do everything they can, but O'Brian is reluctant to get involved, telling the others he didn't sign up for dangerous work. He leaves the others to stem the tide of destruction. Due to the chaos and the fires people are setting, J'onn hangs back, attempting to locate Superman. The rest of the league mobilizes and spreads out through Metropolis, handling looters and rioters, and runaway vehicles. The Flash is injured as a result, and rescued by Green Lantern. As Green Lantern flies his friend to safety, Boom Tubes open up in space.
J'onn telepathically locates Superman passed out in a Kansas cornfield on Earth. Superman wakes, weak and exhausted. J'onn apprises him of the situation, and tells Superman what's going on. Palmer comes over the commlink to point out that there are now alien ships spreading out over major capitals. Realizing it's no accident, Superman asks J'onn to have Diana meet him at the White House and takes off.
In capital cities all over the world, alien warships lay waste to seats of power. Several world leaders are teleport-kidnapped as their defenses are decimated. Superman and Diana touch down at the White House to find The President being ushered to Air Force Two. Superman asks what the league can do to help, but they are interrupted when Air Force Two explodes. Parademon soldiers burst through the smoke, decimating the Secret Service. Superman and Diana are momentarily stunned, and several Servicemen lose their lives. Then Superman moves to stop them as Diana protects The President. Kalibak teleports into the scene and blasts Superman. The two of them do battle, with Kalibak eventually winning due to his ruthlessness, burying Superman under the flaming remnants of Air Force Two. Diana is also defeated as she tries to protect the President. Kalibak's warship rises toward space, leaving behind a burning White House.
Superman claws his way free of the wreckage, and J'onn contacts him telepathically. Superman tells J'onn what has happened, and The Manhunter tells Superman that he is in no shape to go after the aliens alone, and that he should return to the Watchtower so the league can assess the situation.
In the Moon Complex, Kalibak arrives with his captive world leaders, and attaches translator devices to them. Darkseid addresses the world leaders, asking them to surrender Earth to prevent the suffering of humanity.
Superman returns to the Watchtower, where Palmer, J'onn and Kyle are watching images of the destruction the alien attack caused. They have tracked the warships on a trajectory toward the Moon, and informs Superman of the Apokoliptans use of teleportation systems to kidnap the world leaders effectively. Superman is heartsick at his failure, and says they must leave then to rescue Diana. He wants to take J'onn and Green Lantern, but Kyle refuses to go, afraid after what he's seen unfold. This disgusts J'onn, but he and Superman head out, leaving Kyle behind, hating himself.
Superman and J'onn soar over streets still crowded with looters, National Guard and cops, and J'onn, who can feel all the chaos going on, muses about humanity's inability to care about each other. Superman points out that humanity has better sides, but J'onn talks about his homeworld Mars before it's destruction, and wonders if the league has taught them anything worthwhile with their presence. Superman doesn't have an answer for him. Silent, J'onn and Superman climb into space.
In the Watchtower Sick Bay, Kyle goes to see Wally, who is healing. He asks Wally how he can put his life on the line without any amazing powers, and Wally tells Kyle about his uncle Barry, who died saving the world. He doesn't see how he can do any sense. He also mentions Superman as an inspiration. When Kyle reveals that he's not sure he deserves the Power Ring or the role of Green Lantern anymore, Wally tells him it's just a matter of will, and asks him not to give up. Kyle isn't so sure anymore.
In the Moon Complex, we find ourselves in a high-tech, dungeon-like laboratory, where Desaad has Diana wired into a large brainwashing device, and is torturing her. Darkseid enters, watching for a moment, and asks Desaad if the Anti-Life suggestion has taken hold. Desaad replies that Diana is strong, but will be broken. Darkseid asks him to leave them, and turns off the machine, calling Diana beautiful. He tells her she was created to wage war, but she defies him, saying she was meant to bring peace. Darkseid explains his plans for Earth to a horrified Diana: Because humans are creatures of conflict, he will unlock their darkest side. He will destroy most of Earth's population to conquer the planet, and then breed and brainwash and twist those who remain to serve as his slaves and soldiers in his struggle against New Genesis and to aid in his conquest of countless other worlds. He tells Diana that the Anti-Life, which is pure suffering, will triumph over anyone's will. Diana tries to resist, but Darkseid turns the machine higher, reveling in her suffering.
Elsewhere, Kalibak is watching holo-footage of a massive, brutal battle in a shining city on New Genesis. Desaad enters and praises him, then proceeds to point out how much Darkseid overlooks Kalibak, despite his great accomplishments. He hints that Kalibak will never know his full potential until Darkseid is dead, and tells Kalibak that together they could carve out a new future for the universe.
In the Monitor Room, Palmer and O'Brian discuss the nature of power and helping others with it. Palmer points out that the firemen and cops dealing with firesin Metropolis haven't got any superpowers. He tells O'Brian he can mold himself into any kind of person he wants to be, but that he could do a lot of good. O'Brian isn't used to doing good. He's used to looking out for himself. Elsewhere, alone, Kyle tries to recharge his Power Ring with the hidden Power Battery, but can't summon the will to complete the process. The ring dies, as does the Battery, and an angry Kyle removes the ring and pockets it.
In the Moon Complex, Darkseid summons Kalibak to him to tell him he has overlooked his accomplishments, and that he is becoming proud of him. He tells Kalibak he will stay on the Moon to oversee the invasion of Earth. Kalibak, stunned and touched, hesitates, but tells Darkseid there is something he should know.
Superman and J'onn arrive at the Moon Complex, scanning it with their powers. After taking out initial resistance, they find their way to Desaad. Superman threatens Desaad unless he reveals Diana's whereabouts, and J'onn steps in removes the information from his mind. J'onn makes Desaad open Diana's containment, and Superman frees her. But the brainwashing has taken effect, and Diana is reduced to anger. She attacks Superman and J'onn, raging against Superman for his weaknesses, and is subdued only when J'onn shuts down her mind. J'onn tells Superman he's located the captive world leaders, and he and Superman set off to find them, with an unconscious Diana. But not before Superman destroys the brainwashing machine.
The leaguers encounter Darkseid and dozens of his Parademon soldiers. Darkseid confronts Superman, telling him that he wishes to avoid bloodshed. As a token of goodwill, he will allow the leaguers to leave, and will return the world leaders as well. He asks Superman to convince the world to surrender in order to avoid massive slaughter and suffering. Superman tells him the Earth will never surrender, and Darkseid says that it will have to suffer if it does not. He gives them one chance to avoid massive suffering, then tells Kalibak to have the world teleported home, as they're of no further use. He tells Kalibak that if Earth is not surrendered to him, they will attack Metropolis, where Earth's Gods themselves live.
In the Watchtower, Diana sleeps, surrounded by Superman, J'onn, and Palmer, who has just finished running tests on her. He tells them she's be fine physically. Diana wakes, and angrily tells SUperman he has placed the world in jeopardy, that he should have killed Darkseid and his forces on the Moon. Superman, shaken, leaves, and J'onn follows. J'onn tells Superman he will do everything he can to heal her mind, revealing that Diana has been reduced to base instincts via the brainwashing. Superman isn't sure how this fits into Darkseid's invasion plans, but decides he has to warn the world of Darkseid's intentions anyway. He leaves, and J'onn returns to the sick bay.
The President, Amanda Waller, and the Joint Chiefs are aboard Air Force One when Superman boards the plane in midflight. He tells them of the invasion, and is shocked when they tell him about the earlier security breach. Trust begins to crumble. Superman leaves, wishing the government leaders luck.