My personal idea is a Modern Guardian of the Galaxy movie, based around their formation in Annihilation Conquest. Instead of going too far into each character's individual background, it would center around Star-Lord, a space hero who fell from grace due to a terrible mishap, and his attempt at redemption, and Adam Warlock, a potential cosmic messiah who is having an identity crisis after his birth. Star-Lord and Warlock would have almost a Spock/ Kirk relationship.
The film would have kind of a Star Wars meets Dirty Dozen feel to it, with the Guardians being a rag tag group of outsiders in the greater marvel cosmic universe. I'd have Nova either cameo or be involved in the movie somehow, and down the road, spin-off a Nova solo movie.