I'd like to see a new blade franchise, reboot style. With a younger (in appearance) Blade. I'd like a new origin, I want Blade to seem like an immortal.
Maybe have him born in the mid 1800's in America, have his mother be a slave that was bitten by a superior vampire, while secretly pregnant with Blade.
Then he's born in a world of destruction and secrecy (the American civil war).
Set the movie in the late 1800's with Blade, who has been training with the vampires but have him realize what he's doing is wrong, and have rebel and show true Independence and growth after he defeats a powerful and dangerous foe, the leader of his old group.
I'd set the next movie, in the mid 1970's, bring in a young (around 22-24) but wise whistler, who further trains Blade(who appears to be 25-28, but is well over 100 years old) and aids him in his ongoing battle of the vampiric underworld, also I'd bring in Dracula as kind of a kingpin, not really the main focus but the one pulling the strings.
And in the next, I'd finally have Blade confront Dracula in today's world, and have to make a dire decision, that would change the world as he knows it.
I would include a scene just like this one.