I wouldn't expect Disney to do much besides make some animated cartoons for their Disney channels and that'll be all. They make 52 episodes get their package ready cancel the show and move on to the next one. I don't see any serious dark stuff like Blade(the fact it has 3 r-rated movies, and a tv show from spike will stop Disney) or Moon Knight being made.
We'll see some the usuals(Spider-man, X-men, Avengers, Iron Man, Thor, Hulk and Fantastic Four) and the maybes(Heros for Hire, New Warriors, Nova)
And maybe one live action show for ABC every few years.
Extra thought here- I could really see them making a Heros for Hire cartoon. As it fits well with they're show The Replacements(Well the basic concept at least), expect its just, Cage, and Iron Fist being called to help people. If made though I would guess they would aim to make it in line with they're other action shows of late(Kim Possible, Jake Long) with more of a lean on the comedy than the action