Sequels Now that we know how X3 ends....

Can sequels work without Jean and Cyke and Rogue??? Gosh that's going to be tough... I mean Gambit really liked Rogue... and that's all but gone... Hellfire club still a possibility... but how does that work without Cyke... it's going to be tough to pull off... maybe they will just focus on the younger Xmen led by Storm and Beast with Wolverine making cameos here and there... it's just that everything we thought about Xmen has been proved otherwise at this point... I don't see X4 happenning anytime soon...