Not really, I mean if I redid highschool now, I'd have much better strategies toward establishing positive relationships, but I helped wreck my highschool experience by my disposition and paranoid mindset at the time.
Early on I was bullied, so as a self-defence mechanism I took on the oddball persona in order to push people away from me, so I have the habit of making off-kilter comments that still pushes people away.
Now that I'm in university, I see that most people around me have secure, established friendships that have been going on for years. I have a hard time breaking that barrier, no real time during class to start anything, and after I just go back home...
Conversationally I'm much more active on boards then with the handful of friends I have, but I still piss people off here as well.