The market for indy comics is very different from the market for mainstream comics. There is some over-lap, obviously, but if you speak to the guys who tend to buy independent works, a lot of them actually look down on colour and claim to prefer B&W. It's horses for courses.
If you're putting your own book together, you might want to do a print run in B&W to keep costs down and make a full colour version available through a POD service like Lulu or Ka-Blam.