See I thought about those two stories as well. But as far as the new stories go, Sam Raimi obviously used some of the source material. GG, takes serium, goes nuts, finds out who Spider-Man is, and throws girl friend off a bridge. Ok. Then Doc Ock, in the middle of a science experiment, looses control of it and has it blow up in his face bonding him to his metal arms. He then sets out to steal money to continue his work. Follows it as well.
Now we get to Sandman. In the comics he was a crimal who while escaping prision crawls through some sand from a radioactive test site. But, has no real motivation for being a bad guy. Venom hates both Peter and Spider-Man for rejecting the Symbiot and Brook for the Sin Eater whowa, Norman for the death of his son (along with a dozen other things). I think that's also why Sandman later became a good guy. He ran out of bad guy motivation.
So again, what might be Sandman's motive? What big story might they refer to?