MJ is the worst she's ever been in any medium (two cartoons handled the "Peter missed my play he promised to watch" stuff much better), Doc Ock should have died after the first punch he received from Spider-Man, artificial intelligence given to appendages connecting to spinal cord somehow gives them their own personality, power loss is far dumber than it is in comparison to Spider-Man tripping and doubting himself for a few pages, or somehow pausing before bigger mutation kicking in.