The Technology Thread - Part 1

That would be handy. My batteries last for **** now.
 
E-cars would be great since if we can get them to work a lot better they'd be much more welcome.
 
After decades, scientists succeed in breeding world's first IVF puppies

I never realized it was actually this hard to do in vitro on dogs before now. What seems like trivial or pointless science actually has a useful benefit beyond just inventing new dog breeds or helping reproduce select dogs like I'm sure most people would assume.

This can help further understand certain human ailments, bring back extinct or near extinct breeds of canine (not just domestic dogs) and help eradicate certain genetic disorders in existing domestic breeds.

Although I can also see some demented scientist creating a Chiamute (Chihuahua/Malamute mix) or something equally bizzarre.

Researchers in the U.S. have created the world's first litter of puppies through in vitro fertilization (IVF), a breakthrough they say could help eradicate diseases in dogs -- and in humans.

Seven puppies were born in July from 19 embryos implanted into a host female dog, according to scientists from Cornell University and the Smithsonian Institution.

"Since the mid-1970s, people have been trying to do [IVF] in a dog and have been unsuccessful," co-author Alex Travis, associate professor of reproductive biology at the Baker Institute for Animal Health in Cornell's College of Veterinary Medicine said in a statement.

Past attempts have failed because dogs have different reproductive systems to most mammals.

The researchers found that if canine eggs were left just one extra day in the oviduct they had a much better chance of being fertilized. And when magnesium was added to the cell culture, it helped mimic conditions inside the female canine reproductive tract, which unlike many other animals helps to prepare the egg for sperm.

"We made those two changes, and now we achieve success in fertilization rates at 80 to 90%," Travis said.

An extra challenge was the small window in which to implant the embryo during the dogs' reproductive cycle. The embryos had to be frozen while the researchers waited for the right moment, which only happens once or twice a year.

What happens next?


The pups, healthy and now five months old were bred from a combination of pairings. Two of the puppies are from a beagle mother and a cocker spaniel father, and the other five were from two sets of beagle fathers and mothers.

The techniques used to create the pups are vital for progress in saving endangered dogs, curing diseases prevalent in certain breeds of dogs, and researching cures for human conditions.

Dogs share more than 350 similar heritable disorders and traits with humans -- almost twice the number as any other species -- according to the study, published in the journal Public Library of Science ONE, meaning that the research could be invaluable in furthering our understanding of human ailments.

The simple ability to breed dogs via IVF could help save endangered species, including the African painted dog, otherwise known as the African wild dog. As few as 3,000 are believed to exist in the wild, in parts of south Africa and the southern part of East Africa.

And the opportunity to work with genes could help more common breeds, for example, golden retrievers, who suffer a higher incidence of lymphoma than most other dogs.

Louise Brown Oldham, the first human born by IVF -- or so-called "test tube baby" -- was born in 1978. Since then the practice has become widespread for couples who have difficulty conceiving naturally.
CNN
 
Behold, the catalog of cellphone spying gear the feds don’t want you to see
Leak sheds light on cell-site simulators used by military and intel agencies.

It's technology the Feds and police use to abuse our rights to privacy and not being in a police state...

A secret catalog of cellphone spying gear has been leaked to The Intercept, reportedly by a person inside the intelligence community who is concerned about the growing militarization of domestic law enforcement.

Among the 53 items are the now-familiar Stingray I/II surveillance boxes. They're billed as the "dragnet surveillance workhorse [that] has been deployed for years by numerous local law enforcement agencies across the United States." It has a range of 200 meters and sells for $134,000. A chief selling point is the "ready-made non-disclosure agreements from the FBI and Harris Corp. [that] will provide a pretext for concealing these features from the public." The listing also touts Harris' "next-generation Hailstorm, a must-have for cracking the 4G LTE network."

Besides manufacturing the Stingray brand of surveillance gear, Harris once employed a spokesman name Marc Raimondi. According to an Intercept article accompanying the leaked catalog, Raimondi is now a Department of Justice spokesman who says the agency's use of stingray equipment is legal.

The REBUS Ground Based Geo-Location, meanwhile, has a model small enough to fit in a backpack and "provides limited capability to isolate targets utilizing Firewall option." Almost a third of the entries advertise equipment that the Intercept said has never been publicly described before. The National Security Agency is listed as the vendor of one device, while another was designed for use by the Central Intelligence Agency, and a third was developed for a special forces requirement.

The Intercept reports:
A few of the devices can house a “target list” of as many as 10,000 unique phone identifiers. Most can be used to geolocate people, but the documents indicate that some have more advanced capabilities, like eavesdropping on calls and spying on SMS messages. Two systems, apparently designed for use on captured phones, are touted as having the ability to extract media files, address books, and notes, and one can retrieve deleted text messages.

Above all, the catalogue represents a trove of details on surveillance devices developed for military and intelligence purposes but increasingly used by law enforcement agencies to spy on people and convict them of crimes. The mass shooting earlier this month in San Bernardino, California, which President Barack Obama has called “an act of terrorism,” prompted calls for state and local police forces to beef up their counterterrorism capabilities, a process that has historically involved adapting military technologies to civilian use. Meanwhile, civil liberties advocates and others are increasingly alarmed about how cellphone surveillance devices are used domestically and have called for a more open and informed debate about the trade-off between security and privacy—despite a virtual blackout by the federal government on any information about the specific capabilities of the gear.

“We’ve seen a trend in the years since 9/11 to bring sophisticated surveillance technologies that were originally designed for military use—like Stingrays or drones or biometrics—back home to the United States,” said Jennifer Lynch, a senior staff attorney at the Electronic Frontier Foundation, which has waged a legal battle challenging the use of cellphone surveillance devices domestically. “But using these technologies for domestic law enforcement purposes raises a host of issues that are different from a military context.”
Federal authorities have worked hard to prevent the public from knowing much about the cell-site simulators used by law enforcement. Today's leak is a stark counterpoint to that secrecy.
Ars Technica
 
Reusable, sugar-based polymer purifies water fast
Can pull out pharmaceuticals, chemicals used to make plastics, and more.

This stuff can be potentially huge for developing nations and waste water management.

Clean water is essential, yet in certain parts of the world, it's very difficult to obtain. Unfortunately, our limited water resources are being polluted by chemicals from industrial plants, pesticides, pharmaceuticals, and more.

Adsorbant materials composed of carbon are often used to remove many of these organic pollutants. However, they act slowly, typically miss hydrophilic micropollutants, and can be difficult to reuse.

Scientists working on developing inexpensive materials that can purify water quickly have been working with an insoluble polymer called β-cyclodextrin (β-CD)—a big loop of linked sugar molecules. Recently, they've discovered a way to cross-link β-CD using aromatic groups forming a porous, cross-linked complex. The porous, cross-linked β-CD has an increased surface area that significantly speeds the removal of pollutants.

Assessing purification

The team tested how well the new material could sequester organic micro pollutants, using Bisphenol A (BPA) as a model pollutant. (BPA is a component of plastics that has raised significant health concerns over the past decade.) The team assessed a variety of activated carbon adsorbents and a few variations of β-CD. All materials eventually removed the majority of the BPA from a solution.

However, they found that the porous, cross-linked β-CD removed the BPA much faster than all the other materials tested—it reached 95 percent of its final uptake in a mere 10 seconds. In general, the material exhibited purification speeds 15 to 200 times faster than other β-CD based materials and commonly used activated carbons materials.

The team compared β-CD to the activated carbon materials currently used for purification using a mixture of organic micropollutants that modeled real-life environmental conditions. The pollutants in this mix include model aromatic compounds, pesticides, plastic components, and pharmaceuticals. The new material again outperformed the leading activated carbon adsorbent.

Reusable, too

The scientists also explored the ability to reuse the material. They found that BPA could be easily removed from the material by rinsing the polymer in methanol at room temperature. They repeated the process five times and saw negligible decrease in performance compared to freshly synthesized polymer.

A cost analysis of the material indicated that this polymer can be sold at a comparable or cheaper price than the current activated carbon adsorbents. Future studies should test this material in various forms, such as microparticles or membranes, in order to fully maximize its purification potential.
Ars Technica
 
A New Google Extension Will Change Every Mention Of ‘Pro-Life’ To ‘Anti-Choice’

A highly controversial but I think necessary discussion that has been ignored for too long. They make a compelling argument for why this change is needed, even if you don't change your stance on abortion, this is more accurately reflecting the discussion, not altering the words to imply the opposition is for abortion only.

The pro-life phrasing has this moral implication that it is superior even though it is not necessarily true.

If you’ve noticed that the politicians who claim the “pro-life” label are often singularly focused on restricting abortion, and aren’t necessarily working on other policy proposals that could save lives, there’s a new Google extension for you.

An extension released this week will change every mention of “pro-life” to “anti-choice” once it’s added to a Chrome browser. “Tired of seeing the fraught term ‘pro-life’ used ubiquitously and incorrectly, we conceived of this extension to shift the language of the discussion towards a more accurate framework,” explains an online description of the “Choice Language” tool.

The extension was created by an activist who wishes to remain anonymous; she partnered with the National Institute for Reproductive Health Action Fund to release it to the public this week.

“We thought it was a really interesting and creative idea,” Andrea Miller, the president of NIRH, told ThinkProgress. “We agreed with her that the language in this discussion really matters.”

Miller said her organization shares the activist’s concern over the “pro-life” label, particularly when it’s used to describe legislation that ultimately serves to restrict women’s access to reproductive health care. She doesn’t think that’s a fair way to characterize those policies.

“These laws are undermining the ability for people to make decisions about their family, their parenting, their health care, their future — and we believe that allowing people to make those decisions is about respecting their life,” Miller said.

The difference between “pro-life” and “anti-choice” may not seem like a big deal to some internet users. But reproductive rights proponents often argue that the language we use to talk about issues related to abortion can have a bigger impact.

For example, pro-choice women who decide to start families say it can be hard for abortion opponents to understand why they would want babies of their own. The head of NARAL Pro-Choice America, Ilyse Hogue — who gave birth to twins last year — once recounted to the Washington Post that her visibly pregnant belly attracted looks of shock and surprise in meetings with the leaders of major anti-abortion organizations.

The assumption is that people who support abortion rights must not like or want children — as if the viewpoint on the other side of “pro-life” is “anti-baby.”

“If you state that something is pro-life, then the opposite of that is obviously quite demonizing,” Miller pointed out. “It’s incredibly loaded.”

As a whole, the shorthand that Americans use to describe their stances on abortion rights is imperfect. Though the “pro-life” and “pro-choice” labels have defined the national conversation about abortion for decades, there’s evidence that a growing number of Americans don’t identify with these terms — and trying to categorize people into these two groups could be misrepresenting how the public actually feels about this issue.

For now, Miller can’t think of any better labels to use. But she’s hoping that the new Google extension will help open up a larger discussion about the nature of the legislative effort to restrict abortion, and the words our society uses to describe it.

“The fundamental challenge is that we look for labels that are very short and simple, but this is not a short and simple issue,” Miller said. “I’m not sure we’ll ever find the magic answer. But we want people to take a moment to stop and think, hey, what is the agenda here, and based on that agenda, where do I really fall?”
Think Progress
 
F-35 radar system has bug that requires hard reboot in flight
Virtual BSOD for radar software could delay USAF's full deployment of fighter.

This is what used to be called a boondoggle but the military is dogged in their determination they did not make a mistake investing $1.1 trillion (lifetime) in a system that has years of technical failures and massive cost overruns (the literal definition of a boondoggle) but also requires the pilots to restart the flight computer in the air to fix it.

In an episode of CBS' techno-procedural series CSI:Cyber that aired in January, pilots were forced to power off and power back on an airliner's flight computer to regain control from a hacker. As preposterous as that cold-boot of avionics sounds, it's something that test pilots have had to do with the F-35A "Lightning II" Joint Strike Fighter's radar system—not because of a hack but because of a software problem that causes the radar to degrade or stop working entirely.

IHS Jane's reports that an issue arose in late 2015 with the F-35's AN/APG-81 active electronically scanned array (AESA) radar system, built by Northrop Grumman for the Lockheed Martin-led F-35 program. The software planned to be used in the F-35A when the Air Force declares its "initial operational capability" (IOC) with the fighter later this year—revision 3i—has a major flaw. As Air Force F-35 Integration Office Director Major General Jeffrey Harrigian told Jane's, that flaw affects "radar stability—the radar's ability to stay up and running. What would happen is they'd get a signal that says either a radar degrade or a radar fail—something that would force us to restart the radar."

Harrigan said that Lockheed Martin has discovered the cause of the problem and has diverted developers who were working on the next increment of the F-35's code to fix it. A patch is expected by the end of March. But if the fix is delayed, it could push back the Air Force's IOC declaration, which is currently expected some time after August of this year.

The Marine Corps gave the F-35B, the vertical take-off and landing version of the Joint Strike Fighter, an IOC declaration last June. The F-35B is running an earlier iteration of the software, and there have been no indications of a problem with the radar system in Marine aircraft.

The software version being run by the Marine Corps—Block 2B—contains what the F-35 office describes as "more than 87 percent of the required code for full warfighting capability." But it was plagued with other issues, and some tests were abandoned to get the software out in time for the June 2015 rollout. And the F-35B currently has a reduced number of weapons that it can be armed with because of missing software and integration work.
Ars Technica
 
Napster Founder Plans to Offer New Movies at Home For $50 Per Shot

Someone comes up with a sane solution to internet piracy only to immediately ruin it with an outrageous price tag and restrictions.

Straightforward availability of content is often cited as a reason for people pirating content. Whether it’s geo-locked movies on Netflix or TV shows premiering in the United States before less lucrative markets, reasons for obtaining content without permission begin to pile up.

One of the main availability issues is caused by theatrical windowing, the period in which the latest blockbusters play exclusively in theaters before hitting consumer platforms. During these weeks and months the public is expected to head off to the cinema and pay relatively large sums of money to watch the movie in the company of hundreds of others, or go without.

While this is an attractive proposition to millions of people every year, others prefer to enjoy content in their own homes but during the theatrical window there is only one way to do that and it involves breaking the law. However, if Napster co-founder Sean Parker has his way, watching first-run movies without leaving the couch might soon be an option.

According to Hollywood sources, Parker is currently working on a new project which will offer brand new movies in the home on the date they’re released in cinemas.

Called Screening Room, the project envisions the installation of a special set-top box in the home for a not unreasonable $150. However, when consumers want to watch a movie they will have to shell out $50 for the opportunity to view it once during a 48 hour period.

For the single person at home or those on a date, $25 to $50 each sounds like a lot of money. That being said, throw in a family with a few kids or a bunch of friends on a Saturday night, all of a sudden it’s much less than $10 each which is an altogether more interesting proposition.

Also on the upside is the avoidance of the other ancillary costs associated with visiting a theater. There’s no fuel to reach the location, no parking charges, no expensive food and drink, and no expensive movie memorabilia to spend money on. In fact, the more one thinks about it, the better value $50 sounds.

Of course, while all this money saving might be good for the public it sounds bad for theater chains. However, Screening Room is said to have a solution. According to a Variety report the company might be prepared to cut exhibitors in on the deal, handing them up to $20 per screening. Furthermore, customers who pay $50 to watch at home would then get two free tickets to watch the movie in the cinema, a clear opportunity to make some money on top.

Needless to say, distributors will also demand a cut and it’s being reported they would receive a 20% share of the $50 outlay. For their part, Screening Room is looking at taking just 10% ($5) from each viewing.

While still in the early stages of development, it’s reported that Screening Room representatives have been meeting with all the major studios with Universal, Fox and Sony showing a lot of interest. According to sources, the company is close to doing a deal with AMC.

But not everyone is happy, far from it. According to comments made to Deadline by a pair of major studio distribution executives, Screening Room’s proposals are of huge concern.

“This news is so damaging, I can’t tell you right now how unhappy I am,” said one.

Another expressed a more apocalyptic view.

“It would be the beginning of the end, and half of the theaters in this country would close,” he said.

So, on the one hand sits Screening Room, with plans to fill a huge gap in the market while disrupting it significantly. On the other sits some frightened industry players who see the fledgling company as the modern equivalent of the Betamax Boston Strangler.

At home sit hungry consumers, some looking to outlay $50 per shot and others wondering if the incoming movies will be easy to copy. Apparently Screening Room has secure anti-piracy technology in place – but they all say that, don’t they?
Torrent Freak
 
GM mosquitoes clear an FDA hurdle for Florida release, locals angry
Engineered bugs could block spread of Zika, dengue, yellow fever, and chikungunya.

This is biogenetic technology but still nonetheless technology. And something potentially hugely beneficial if it proves successful. Of course people get a whiff of the words "genetically modified" and freak out even though this has been thoroughly tested and re-tested to make certain there is no impact on either humans or the environment outside the non-native mosquito population.

Also, I have no idea why the completely nonoffensive scientific name of the mosquito in question is censored.:huh:

Genetically engineered mosquitoes that have been under regulatory review for the past five years have passed one of the last remaining hurdles to gain approval for release in a field trial, the Food and Drug Administration announced Friday.

Oxitec’s OX513A ***** aegypti mosquito would pose no significant threat to the environment or to people in Key Haven, a community in the Florida Keys where the company proposed the trial, the agency announced in a preliminary finding. The initial judgment of “no impact” from the environmental assessment will be followed up by a 30-day window for public comments. Then, the FDA will make a final decision. If the agency confirms the preliminary green light, the mosquitoes could be released shortly after.

“We look forward to this proposed trial and the potential to protect people from ***** aegypti and the diseases it spreads,” Oxitec’s Chief Executive Officer Hadyn Parry said in a statement.

OX513A male mosquitoes are genetically modified to pass on a lethal gene to offspring, thereby crippling the local wild population of ***** aegypti. These mosquitoes, which in the US are mostly found in Southeastern states, have the potential to transmit Zika, dengue, yellow fever, and chikungunya viruses. Field trials of OX513A are already underway in Brazil, the Cayman Islands, Panama, and Malaysia.

Not everyone in Key Haven is happy with the FDA's decision. "People don't want to be guinea pigs," Mila de Mier, a Key Haven resident, told CNN. "There has been no acceptance from community members. If the local and federal government fail to protect us and our wishes, our last option will be to trust the judicial system and bring it to the court. A legal battle is an option at this point."

The area of Key Haven, a community of fewer than 500 homes about a mile east of Key West, was selected after the areas suffered from a dengue outbreak in 2009 and 2010.

In comments to CNN, Oxitec’s Parry acknowledged that there was not full support from the Key Haven community, but noted that the scenario is common for public health interventions. He also expressed urgency to get the trial going in light of the spread of Zika virus. “The sooner we can get going and show what we can do, the sooner we can make a difference in the fight against this virus,” he said.

The window for mosquito population booms in Key West is from April to September.
Ars Technica
 
London to NYC in just 3.4 hours? A roundtrip will set you back $5,000
Virgin Galactic to go where the Concorde failed, into commercial supersonic flight.

From 7 hours to just 3.4 hours is quite an improvement. A bit pricey but I think it's worth it considering how much hell it must be to fly traditional for that many hours.

After more than a decade of dormancy commercial supersonic flight may soon return to the skies. The Soviet Tupolev supersonic aircraft flew just a few dozen flights back in 1977, and the Concorde, flown by British Airways and Air France, retired in 2003 after a fatal accident three years earlier that compounded economic problems.

But now Richard Branson and his Virgin empire are ready to try it again. According to The Guardian, Branson has signed a deal with an American firm to bring commercial supersonic travel to the airways, beginning with trans-Atlantic flights between London and New York City.

The agreement brings Branson's Virgin Galactic into a partnership with Colorado-based Boom, founded by Amazon executive Blake Scholl. Virgin Galactic, according to a company spokeswoman, will provide engineering, design, operations, and manufacturing services, along with flight tests at Virgin's base in Mojave, Calif. It will then have an option to buy the first 10 airframes from Boom.

It's an interesting arrangement that further expands the activities of Virgin Galactic, which is trying to find new ways to put people and satellites into space. The company recently debuted the second version of its spaceship, VSS Unity, that it hopes will one day fly customers paying $250,000 into space for a brief weightless experience. Virgin Galactic also has begun modifying a Boeing 747-400 aircraft it intends to use to boost small satellites weighting up to 450kg into orbit, perhaps before the end of 2017.

Now the company will move into supersonic territory with Boom, which is located in a hangar just south of Denver at Centennial Airport. On the company's web site, Boom says its aircraft will travel at Mach 2.2—faster than the Mach 2.0 of the Concorde and far faster than the Mach 0.85 of many commercial airliners. A $5,000 round trip will take just 3.4 hours, the company says, cutting the seven-hour travel time between London and New York by more than half.

"At Mach 2.2, you don't merely save hours," the company advertises, on its site. "You can travel across the Atlantic or Pacific, get business done, and be home the same day. Spend more nights at home."

Former astronaut Mark Kelly has signed on to Boom's leadership team.

The Virgin Group spokeswoman said the partnership remains in its "early days," although Boom says it could begin test flights at the end of next year. The new partnership gives Branson's Virgin Galactic three areas in which it is now pushing modern flight: launching passengers into space, using a former commercial airplane to launch rockets into space, and now shuttling people across the Atlantic while breaking the sound barrier. It is not clear whether any of these ventures will prove profitable, but there is certainly no lack of ambition.

And despite the failure of the Concorde, Virgin and Boom are not alone in seeing the potential for commercial value in supersonic flight. In President Obama's latest budget request for NASA he has sought an increase of $3.7 billion over the next decade for aeronautics, with the enabling of supersonic flight as one of the program's flagship goals.

In an interview with Ars last month, Jaiwon Shin, the associate administrator for NASA’s Aeronautics Research Mission Directorate, said one of the biggest barriers to viability is a complete ban by the Federal Aviation Administration and other international flight agencies on supersonic flight over land due to sonic boom issues.

However, Shin said, NASA has developed designs that break one big shockwave into several smaller shocks as the aircraft passes through the sonic barrier. If Congress grants the funding NASA has requested, the agency will build prototypes to fly over developed areas. Much of that testing could be done from Edwards Air Force Base, near Mojave, where Virgin will be working on developing the Boom aircraft.
Ars Technica
 

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