here's a good article on the game from IGN:
Before we kick into the gameplay specifics, it's important to let a disclaimer fly right off the bat. Trauma Center: Second Opinion, is what developers like to call (and we hate hearing the name already), a "Wii-make". The adventure is in no way a port when looking at the DS graphical presentation in regards to the Wii version, but the gameplay, story, characters, and missions are still in tact from the original game. In typical launch title fashion, Atlus was most certainly rushing this one out the gate, and for that reason is making use of an already solid design, changing only what needs to be changed for the Wii version.
That being said, the game is spectacular for what it is, and following the age-old formula of "if it ain't broke, don't fix it", Atlus stayed very true to the original design, using graphical improvements and a few new items (and interactions) to make the game feel fresh and new, while still playing true to its original form. Players will take the role of Dr. Stiles, a hot-shot rookie surgeon that quickly climbs the ranks to achieve near super hero status in the operating room. Using the Wii-mote and nunchuck combination, players will manipulate more than a dozen different items, ranging from a scalpel, defibrillator, syringe, antibiotic gel, and good ole' thread and needle to seek out and attack nearly any surgical nightmare out there. To keep the game from feeling stale, many of the moves are done with the Wii-mote's more intricate control, having players actually use the A and B buttons to pinch with the tweezers, or rub the controllers together and shock a patient back to life with a jot from the "defib paddles". In addition, the final chapter of the game is entirely new, and while that isn't going to be a huge deal-breaker for otherwise sour apples that won't settle for anything less than an all-new game, fans of the original can still rest assured that there's a bit more to the story than just a token port.
And in all honesty, it doesn't matter that Trauma Center: Second Opinion is, at its roots, a double dip. The gameplay is so amazingly solid, people will instantly forget this is an upgraded version of the DS game, and instead focus on how awesomely intuitive the design can truly be. And when it came to playing the game in a crowd, we witnessed first hand just how powerful the Wii can be when delivering addictive, simple entertainment. All it took was for a passing player to reach out and shake the arm of the "doctor", forcing the player to jab a chunk of glass into his patient, rather than slowly removing it, and anyone watching the action was cracking up at the scolding the unsuspecting player received from the game. It wasn't simply the fact that the game was deep or immersive in its control (even though you know that's still true if you've played the DS version), it was the chance to finally play the game with spectators, knowing that every move you made was being projected on the big screen, rather than a three inch touch panel. We can definitely see Trauma Center as a game that, while one player, is entertaining for multiple people at a time simply because of the amount of stress and tension in the game.
Oh, and before we let you go, consider this. It may have been tough to make that final crucial cut on the DS version, but when we compare stylus control to our actual hands using the Wii-mote as a virtual scalpel, Trauma Center: Second Opinion is more challenging than ever, and it definitely takes the series to an all-new level of immersion and control. Simply put, you better have a steady hand and nerves of steel for this one.
http://wii.ign.com/articles/732/732909p1.html