The Final Fantasy series (and, really, any turn-based Japanese RPG): These always feel more like movies with interactive segments interspersed throughout the cutscenes rather than games, plus I'm not a fan of turn-based games in general. They feel very dry and uninteresting to me. Also, I'm really not a fan of most of the stories of the games. I kind of have this thing about anime being overly philosophical and lacking any subtlety whatsoever in delivering its philosophical messages, and that definitely comes into play in the stories of Final Fantasy for me.
World of Warcraft: I get addicted enough to normal games and am only freed from that addiction when the game mercifully ends and I can go back to real life for a bit. I'd hate to imagine my life with an endless MMORPG in the mix. Plus, paying for a game forever sucks. Plus, the mechanics of MMOs are ******ed to me, given that the game can practically play itself, you basically need big groups of people to accomplish anything worthwhile, you have to engage in hours and hours of mindless bulls*** to get experience and level up, etc. Basically, everything about WoW runs against my personal preferences in games. Well, except that there aren't cutscenes, only I hear Wrath of the Lich King just added those, as well.
Metal Gear Solid: Not a fan of stealth as the primary component of games. I haven't got the patience for it. If I do play a stealth-based game, I tend to prefer stuff like Splinter Cell and Thief, too. Also, MGS indulges in a lot of the Japanese game conventions I mentioned earlier--interminable cutscenes, inelegantly told stories that beat you over the head with their philosophizing, etc. I played MGS and a bit of MGS2 out of some kind of imagined obligation because I thought everyone who owns a console needs to play the series, but then I realized that I just didn't enjoy it at all and quit.