First let me commend you for your lengthy story. It is obviously a great passion of yours and it took some serious fortitude to post your work on a site devoted to fans, superfans, and ultra-mega-superfans (I myself fall into the second category).
Now to get into it:
As action-packed as this was, I really do not think it would be a successful movie. A comic arc, yes. You have too many characters involved in a story that is only supposed to last two/two and a half hours. Things seemed rushed. The success of the first two Spider-Man films was the simplicity of the characters. The third fell short because of the complexity of the villains. I would pick one strong villain and focus on him, and it might help your story to stand out if you picked a villain that isn't suspected to appear soon.
And the villains just didn't strike me. The two symbiotes were odd. We've already seen Venom and it is highly unlikely that we'd see another alien.
I also think that in the next film Peter and Mary Jane will be getting married. Their relationship is strong enough now that it is the next progression. That's not to say that there won't be problems for the two of them to overcome.
I might also suggest that in future drafts you correct some grammar problems as well as your issue with "Spider-Man" (as previously stated). Honestly, if you are going to post something on a message board read by Spidey fans, it should only go to reason that in something formal like this the main characters name should be spelled correctly. I know it seems ridiculous, but it is something that should not be disregarded in such company.
Otherwise, I found this a good read. It was entertaining without being pushy. Yes, some of the dialogue was not in character, but it is a first draft, right? Things always tighten up in rounds two and three.
Some suggestions if you plan to continue in this endeavor:
-Pick up a couple of screenwriting books. They can help you without you ever realizing it.
-Read some screenplays. There are tons of websites with free screenplays that you can read of your favorite films. See how the pros do it.
-Don't be afraid to cut your own work and piece it back together; it may come out completely different than you intended but it may work.
Take care and keep writing.