If there was no pandemic I'd say something similar to Jurassic World. Now I'm thinking closer to Far From Home.
Better domestic box office than FFH, international will be a less due to closures and fear of the new variant.
I "think" that's about right, but I'm maybe a little bit more optimistic. This is anecdotal, but my go to theater is the Cinemark XD 18 at the Howard Hughes Center in Los Angeles. In the past, I've checked the available seating for the mega movie events like IW, EG, TLJ, etc. In those movies virtually everything was sold out and the only seats available were near the screen on the sides. In this particular case, the Friday evening shows look "sorta" that way. There are, however, a lot of first and second row seats available (in the XD theater) and the 11:30AM still has many, many good seats left. On Saturday, there are a lot of good seats available; most aren't even bought yet except for the XD theater which has a few, single good seats left and a lot for the evening showing.
It's somewhat anecdotal, but it doesn't have the same feel as the big Avenger or Star Wars movies. You literally had to wait until the weekday before you could get tickets and even then, there weren't that many good seats to be had. Part of this could be explained by this being LA and you have to be fully vaccinated before you can even get into the theater so that could discourage a lot of people from going.
My guess would be maybe 160-180M OW. We'll see soon enough. As I said before, we're really missing a lot of data points. We haven't had a huge, mega movie during the pandemic and because of that, there's more guesswork than usual. I'm usually pretty good at hitting numbers, but there are a lot of unknowns here.
FFH had tremendous legs and opened during the summer so weekly numbers were really strong. I don't see this movie having FFH legs.
EDIT: I think my predictions are on the high side because I really want this movie to be ultra successful.