Its not so much different, as moving on from what we already have.
I'm talking 100 years later (from Robocop 3) Old Detriot was gone, it was replace by a new Utopian programe which renamed the area as Delta City. We learn that the original Robocop "Alex Murphy" disappeared near 70 years ago which his absense lead to corrupt corporations fund and drive the Delta City's development. Delta City is split into three areas - The Utopia which is a heavy consumer technology advanced society, Industrial Zone which is a large area pumping pollution into the ozone, and The Outcast Wasteland - which is where most of the criminals has been forced to live by the Delta City's police force. For which is where we follow our new protagonist - who ends up in a similar fate to Alex Murphy but are created by a fallen corporation OCP who has secretes of there own. Basically all is not right, the new Delta City is built by the corrupt corporations that are killing the new ozone. It turns out Fallen OCP is filled with former Police officers of Old Detriot and OCP scientist that were made jobless. So new Robocop is tasks to save mankind.