I like season 2: The Neogenic Nightmare and ,season 3:The Sins of the Fathers. Once season 4 rolled around i got lost, as those idiots at Fox started showing the eps out of order. I hope they release the series on dvd by seasons, as they've done with Batman:TAS.
Favorite all time ep was 'Turning Point' i think it was in season 4. It was when the Green Goblin finds out Peter is Spiderman, and Mary Jane ends up falling into one of 'The Spot's' dimensional holes after Spiderman and the Goblins confrontation on the bridge.
One more thing, did anyone else find the whole 'Madam Web' angle a little odd..?