They might play it a bit like the National Treasure franchise, those movies were corny, with some outrageous premise, but fun.
"I'm going to steal the Declaration of Independence" ..."I'm going to kidnap the president of the US",..etc, nonsense. Just up the game even more over-the-top!
She may be steeling things, but it's all in the name of saving them and the world.
Yet the authorities (ACME Detective Agency) don't know this, hence they are in constant pursuit of her.
I hope they keep the whole pulpy look of the character, plus she had some really great over the top deco-punk looking vehicles and gadgets. All in red.
Would love to see all that.
Also I hope Rita Moreno (who played her on the cartoon) gets a cameo.