No, not TINO. I was talking about the fact that original character have been created for film and the audience have been interested thus the familiarity of the characters are moot. You still use the original T-bolts and adapt them appropriately but because they arnt recognizable by the general audience like say Venom and Bullseye (only because they have already appeared on film) just means that like an original film character they would be introduced to the audience through the movie despite have years of development in comics. The original T-bolts were more like Marvel U villains. They moved around more than being nemesis to a specific character, and would be easier to use than Venom and Bullseye after Marvel tries to hunt down and buy backt he rights or sell the rights to Fox so those characters could appear. I didnt even really like the movie-verse Venom (Bullseye could work though, he wasnt fantastic but he could work). And would rather see a whole new group than prior movie run-off appearing in another movie.
Familiarity is a perk, Superman is a bankable name, but if the characters are unknown than they have the same risk factors as an original made for film character which the studios arnt that shy about doing.
There have been plenty of movies where characters start guilt ridden, with skeletons in their closets, at the brink of suicide, with severe emotional problems, etc. all relating to events prior to the events of the movie. Why would that not work now?