The SHIELD show should get Ty Burrell to make an appearance as Leonard Samson. He's already appearing in ABC's Modern Family TV show, it shouldn't be a super-stretch to get him to appear on a fellow network show. Depending on how Modern Family plays out in the next few years, maybe he could even become a recurring character on SHIELD, should it also continue. He could simply appear in his human form, and "eventually" they could hint at possibly having some kind of gamma-radiation accident, or if they want to go darker, maybe Samson actually seeks out some kind of strength enhancement for himself.