Well, there is Moore's Law. There are also a lot of emerging technologies. Still, I think the fully sentient androids are pushing it. That's one hell of a feat. But, hey, it's fiction so I'll suspend disbelief.
By 2048, we'll probably have some really cool stuff, like life-like advanced prosthetics, self-driving cars, powered armor, human cloning, the first generations of genetically engineered babies, etc.
We might have some AI that approach sentience, and we might have believable looking androids, but human-sized robots with minds of their own - that's a long ways off.
I'm kind of waiting for them to discuss how the androids' minds function. Quantum computing, and all that.
I follow a lot of futuristic / robotics blogs.